dewitlab.bsky.social
Computational & Genomics Lab studying 3D genome function and dynamics @ Netherlands Cancer Institute
👤 Joined on 27 November 2024
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@dewitlab.bsky.socialIs euchromatin really “open”? 🧬 Using super-resolution imaging🔬 our new study @natgenet.nature.com reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing for proper transcriptional insulation🚧 🔗 www.nature.com/articles/s41... (1/2)
Show Postsomewhat related - the tendency of SE to cluster in 3D upon cohesin depletion may also be cell type- (or lab-?) dependent work by @angelikafeldmann.bsky.social www.cell.com/cell-reports...
Show PostExcellent thread about the importance of acknowledging and citing community resources: for us its @flybase.bsky.social and the Drosophila Stock Centers
Show PostNew animation of Zinc Finger transcription factors binding DNA. My favorite TF family. 👀 Excited to share more at the #EMBLTranscript Conference next week! - Rendered in Blender with #MolecularNodes
Show PostFor the zebrafish folks, in case you don't know: if you use it -which you do-, you can cite ZFIN as Bradford et al 2022 academic.oup.com/genetics/art... 🧪🐟
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