elphegenoralab.bsky.social
Our laboratory seeks to understand how chromosome structure relates to genome functions
👤 Joined on 17 November 2023
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(5/9) This is despite Polycomb bodies no longer being visible for the most part after depleting cPRC1
Show PostMary Goll, Mathieu Boulard, Olya Yarychivska and I wrote an obituiary, including personal reflections from many of his past lab members, the Bestor phylogeny. www.genetics.cuimc.columbia.edu/news/memoria...
Show PostTim Bestor left us this summer. An extraordinary scientist, epigenetic pioneer, always challenging dogma with a flair for language. For us, above all, he was a generous, loyal, caring and deeply supportive mentor. « Be cool everybody », as he used to saywhen leaving the lab at the end of the day.
Show PostThrough in vitro reconstitution experiments, we surprisingly find that the disruption activity of Srs2 drives the assembly of long and stiff Rad51 filaments when Rad55-Rad57 is present. How can that be?
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