sberry.bsky.social
Harvard Biophysics PhD candidate studying protein evolution with a focus on transporters in the Gaudet and Marks labs. Occasional fiction writer. Proud cat dad.
👤 Joined on 24 October 2023
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@sberry.bsky.socialAn MIT Institute did an internal investigation and found that David Sabatini, a PI, had a sexual relationship with a junior fellow. The institute found that his behavior with her was part of a larger pattern with how he conducted himself among junior staff. It is exceedingly rare for universities…
Show PostI am again reminded of my experience from January of this year where Claude "invented" a new attention mechanism to incorporate mass and spatial relationships from mass spec data into deep models for de novo peptide sequencing. I was exploring new transformer architectures for this task, and
Show PostBinder design is nice and all, but here we have three agents sharing data and autonomously controlling a lab to design enzymes with shifted substrate scopes and high activity! @cobanbrooks.bsky.social @pascalnotin.bsky.social @philromero.bsky.social www.biorxiv.org/content/10.6...
Show PostWhat if AI could interact directly with biology? Congrats to Coban, who gave AI the ability to experiment and learn through feedback. Over 25 autonomous rounds, it uncovered the determinants of enzyme specificity. Give AI the ability to experiment, then get out of the way. doi.org/10.64898/202...
Show Postsee also this work, which helps provide some helpful framing of how novel these phages are: www.biorxiv.org/content/10.6... tl;dr: I believe this work generates only marginally novel phages, which have only a moderate likelihood of working, that decreases the more novel they get.
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