kinasekid.bsky.social
Enjoying life one molecule at a time! / Postdoc @UWproteindesign / ex @Stanford / PhD @LMU_Muenchen / tweeting in English, thinking in Bavarian, coding in Python
👤 Joined on 23 October 2023
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@kinasekid.bsky.socialThrilled to share my freshly "baked" Baker lab paper. We took a bottom-up approach to designing transcriptional regulators. Instead of relying on natural activation domains, we designed compact proteins that recruit specific cofactors. Activators for now, repressors to come!
Show Post1/n Crossover episode! We just released RFD4-Proteina, our latest protein design model - and the result of a year-long collaboration between the Baker Lab and NVIDIA GenAIR (the name says it all…). I hope you’ll agree - the results are astonishing. 🌐 Website: rfd4-proteina.org
Show PostCombine a chemical knowledge, generative modeling, and structure prediction into a pipeline that can design enzymes for new-to-nature chemistry. @zacharywu.bsky.social @alexechu.bsky.social @francesarnold.bsky.social @pushmeet.bsky.social @juewang.bsky.social www.biorxiv.org/content/10.6...
Show PostA late update, but we got celebratory tacos to congratulate Brandon Goldstein on passing his quals (my first student to do so)! He did an excellent job, and I'm looking forward to seeing how his project develops over time!
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