Krishna Mudumbi
krishnamudumbi.bsky.social
• Assistant Professor at Vanderbilt and the Ingram Cancer Center • Studying membrane protein signaling using single-molecule microscopy • Mentorship and science advocacy in all its forms https://lab.vanderbilt.edu/mudumbi-lab/
👤 Joined on 06 September 2023
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- 06 Eyl 2023, 18:42
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@krishnamudumbi.bsky.social - 10 Kas 2023, 00:28
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Protein design doesn’t have to stop at the canonical 20 amino acids! After our work on phosphotyrosine binders, RFD4-Proteina adds phosphoserine and phosphothreonine (below) to the repertoire, with binders that distinguish adjacent H3pS10 and H3pT11 sites in the histone H3 tail!
Show PostCan we design proteins that cut other proteins? Our de novo cysteine protease paper is out in Nature! We designed new folds that cleave peptide backbones, with activity demonstrated in mammalian cells. Paper and code 👇 www.nature.com/articles/s41...
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Hello, Bluesky! Follow along for updates on our work and the researchers we support. New to The Mark Foundation? Check out this video to learn how we accelerate progress in the fight against cancer. #CancerResearch #ResearchFunding vimeo.com/1013135446
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My husband’s tendency to start trying to find something to watch together at 9:40 p.m. is both annoying and somehow endearing. I’m not gonna be awake in half an hour, man.
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See what happens when you shoot the ball.
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