Dazhi Li
@dazhi-li.bsky.social did:plc:wk6gkl4ijtkpdz3jgz5ca57g
Protein scientist | Lipid transport & membrane biology | Ph.D., Yale Cell Biology, Karin Reinisch lab
Bluesky’a katılma tarihi:
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- 32
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- 35
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- 5
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Dazhi Li (@dazhi-li.bsky.social), 10 Aralık 2025 tarihinde katılan bir Bluesky kullanıcısı. 32 takipçisi var, 35 hesabı takip ediyor ve 5 post paylaştı.
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Congratulations to @dazhi-li.bsky.social and members of the Reinisch and De Camilli groups @pdc-lab.bsky.social on their recent work on the structure of Bridge-like lipid transfer protein VPS13C!
Postu gösterExcited to see this study, in collaboration with the De Camilli group @pdc-lab.bsky.social, published in its final format! We resolved the structure of VPS13C and found that it adopts a lipid-transfer-incompetent conformation. We also show that CaM binds VPS13s and may help regulate their function.
Postu gösterThis amazing work by @danialv.bsky.social and Bodan Hu is now out in peer-reviewed form at @cp-cell.bsky.social with a lot of new simulations! Check it out if interested in lipid transport!
Postu gösterReinisch's lab work with the Vanni's lab is online in Cell!! Combining cryoEM and MD simulations, we reveal how the bridge-like lipid-transfer protein VPS13A works with the scramblase XK to deliver lipids to plasma membrane and redistribute them across the bilayer. www.cell.com/cell/fulltex...
Postu gösterLipid scramblases and BLTPs are key to regulate cellular lipid dynamics. Justin Korfhage and I described in-vitro methods to study lipid scrambling by protein insertases and ATG2-mediated lipid transfer on artificial lipid droplets. www.sciencedirect.com/science/chap...
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