Dazhi Li

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• Yale Cell Biology@yalecellbiology.bsky.social08-07-2026 17:31

  Congratulations to @dazhi-li.bsky.social and members of the Reinisch and De Camilli groups @pdc-lab.bsky.social on their recent work on the structure of Bridge-like lipid transfer protein VPS13C!

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• Dazhi Li@dazhi-li.bsky.social07-07-2026 18:57

  Excited to see this study, in collaboration with the De Camilli group @pdc-lab.bsky.social, published in its final format! We resolved the structure of VPS13C and found that it adopts a lipid-transfer-incompetent conformation. We also show that CaM binds VPS13s and may help regulate their function.

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• Vanni Lab at UNIFR, Switzerland@labvanni.bsky.social16-06-2026 00:31

  This amazing work by @danialv.bsky.social and Bodan Hu is now out in peer-reviewed form at @cp-cell.bsky.social with a lot of new simulations! Check it out if interested in lipid transport!

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• Dazhi Li@dazhi-li.bsky.social15-06-2026 15:25

  Reinisch's lab work with the Vanni's lab is online in Cell!! Combining cryoEM and MD simulations, we reveal how the bridge-like lipid-transfer protein VPS13A works with the scramblase XK to deliver lipids to plasma membrane and redistribute them across the bilayer. www.cell.com/cell/fulltex...

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• Dazhi Li@dazhi-li.bsky.social10-12-2025 23:17

  Lipid scramblases and BLTPs are key to regulate cellular lipid dynamics. Justin Korfhage and I described in-vitro methods to study lipid scrambling by protein insertases and ATG2-mediated lipid transfer on artificial lipid droplets. www.sciencedirect.com/science/chap...

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