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Paul Rainey

@paulbrainey.bsky.social did:plc:3btnsaeszcvhqmu4c2fcnm6h

Evolutionary geneticist working with microbes. Absorbed by the curiosity of science and ideas. Department of Microbial Population Biology, MPI for Evolutionary Biology, Plön, Germany & ESPCI, Paris, France.

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509
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274
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86
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Resumo

Paul Rainey (@paulbrainey.bsky.social) é um usuário do Bluesky desde 21 fevereiro 2025. Tem 509 seguidores, segue 274 contas e publicou 86 posts.

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  • Will Ratcliff@wcratcliff.bsky.social

    12/ Unlike snowflake yeast, where one mutation hands you collective reproduction, here selection on collectives builds heredity. A slick model for how genes became chromosomes and endosymbionts became organelles. @charly-evos.bsky.social @paulbrainey.bsky.social doi.org/10.64898/2026.08.05.743067

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  • Will Ratcliff@wcratcliff.bsky.social

    11/ The mechanism is beautiful. Red and green fused with the yeast's native 2µ plasmid into a single replicon, and both lines independently knocked out FLP1, the recombinase that would otherwise cut the chimera back apart. Restore Flp1 and heredity collapses.

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  • Will Ratcliff@wcratcliff.bsky.social

    9/ This next one is super cool. How do unrelated replicators fuse into one heritable unit? Hernandez-Beltran, McConnell, Rogers & Rainey built one from scratch: red and green plasmids in yeast, with selection for yellow cells carrying both.

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  • Private Eye Magazine@private-eye.co.uk

    "You ever notice everything is stupid until our generation adopts it?" From the latest Private Eye, out now.

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  • Jeremy Berg@jeremymberg.bsky.social

    New email to Director Bhattacharya about the unethical hepatitis B study. 1/3

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