Paul Rainey
@paulbrainey.bsky.social did:plc:3btnsaeszcvhqmu4c2fcnm6h
Evolutionary geneticist working with microbes. Absorbed by the curiosity of science and ideas. Department of Microbial Population Biology, MPI for Evolutionary Biology, Plön, Germany & ESPCI, Paris, France.
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Paul Rainey (@paulbrainey.bsky.social) es un usuario de Bluesky que se unió el 21 febrero 2025. Tiene 509 seguidores, sigue a 274 cuentas y ha publicado 86 posts.
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12/ Unlike snowflake yeast, where one mutation hands you collective reproduction, here selection on collectives builds heredity. A slick model for how genes became chromosomes and endosymbionts became organelles. @charly-evos.bsky.social @paulbrainey.bsky.social doi.org/10.64898/2026.08.05.743067
Ver post11/ The mechanism is beautiful. Red and green fused with the yeast's native 2µ plasmid into a single replicon, and both lines independently knocked out FLP1, the recombinase that would otherwise cut the chimera back apart. Restore Flp1 and heredity collapses.
Ver post9/ This next one is super cool. How do unrelated replicators fuse into one heritable unit? Hernandez-Beltran, McConnell, Rogers & Rainey built one from scratch: red and green plasmids in yeast, with selection for yellow cells carrying both.
Ver post"You ever notice everything is stupid until our generation adopts it?" From the latest Private Eye, out now.
Ver postNew email to Director Bhattacharya about the unethical hepatitis B study. 1/3
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