Martin Pacesa

martinpacesa.bsky.social

21 September 2026 10:23

ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi...

vivireber.bsky.social

03 July 2026 14:22

Out now: ATP-competitive inhibitors lock kinases in a pseudo-active conformation and modulate their non-catalytic functions. We show that these on-target, off-machanism effects can cause unexpected phenotypes and how to screen for these effects. Read more at link.springer.com/article/10.1...

Ruth Huttenhain

rhuttenhain.bsky.social

01 July 2026 07:38

Preprint out! We optimized synchro-PASEF for phosphoproteomics & found equivalent biological insights to dia-PASEF despite fewer total IDs. Practical tip: apply retention time summation factor 2 to any PASEF phosphoproteomics data—you'll gain IDs and precision. www.biorxiv.org/content/10.6...

Department of Biology, ETH Zurich

eth-dbiol.bsky.social

20 May 2026 12:58

Honored to celebrate Paola Picotti at yesterday’s Otto Naegeli Prize 2026 ceremony — recognizing her groundbreaking contributions to proteomics and systems biology. An inspiring evening dedicated to scientific excellence and the future of biomedical research... and a great presentation by Paola!

Basavraj Khanppnavar

basurajsk.bsky.social

22 April 2026 17:29

How do cells integrate multiple signals into precise responses? Our study uncovers neuronal calcium sensor proteins as new regulators of adenylyl cyclase 8, linking GPCR-cAMP-Ca²⁺ signaling. @rflorea.bsky.social @dina-sch.bsky.social @psi.ch @eth-dbiol.bsky.social www.biorxiv.org/content/10.6...