vivireber.bsky.social

07 July 2026 16:29

Out now: ATP-competitive inhibitors lock kinases in a pseudo-active conformation and modulate their non-catalytic functions. We show that these on-target, off-machanism effects can cause unexpected phenotypes and how to screen for these effects. Read more at link.springer.com/article/10.1...

Picotti Lab

picottilab.bsky.social

14 January 2026 11:28

We’re delighted to report a global structural proteome analysis within living cells! doi.org/10.1038/s443... #proteomics #structuralproteomics #massspectrometry #structuralbiology #ethz @imsb-eth.bsky.social