const-ae.bsky.social
Scientist at Isomorphic Labs. Previously at UCL and EMBL working with Wolfgang Huber. Biology, ML, Python, R, cancer immunology
👤 Joined on 28 August 2023
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@const-ae.bsky.socialWe wrote a little something, collecting our thoughts and conversations with computational and experimental folks over the years "on technical biases in imaging spatial transcriptomics": shorturl.at/Nljwl
Show PostIt's been 30 years (!!!) since the conceptualization of GWAS. GWAS has driven tons of discoveries, but with recent experimental developments (CRISPR, single-cell omics), we thought it was time to think about how to drive the next 30 years of human genetics. doi.org/10.5281/zeno...
Show PostStoked to share our new perspective on ✨ Trait Causal Models ✨ as the next frontier for human genomics! It was a pleasure to put this together with @jeffspence.github.io and @jkpritch.bsky.social with guidance from @minetoota.bsky.social @jengreitz.bsky.social @marsonlab.bsky.social Thread 👇
Show PostLast week, Biohub, the U.S. Department of Energy, the National Institutes of Health, and new funding partners announced a major expansion of an international effort to generate and make accessible the data enabling predictive AI models of biology. bit.ly/3UhjoxD
Show Post1/ Most genes and variants matter somewhere but look silent in any one cell model. Can we build conditions that reveal phenotypes? With @kanishkadey.bsky.social, we engineer cell states to expose hidden disease biology and trace how genetic risk reaches disease genes. www.biorxiv.org/content/10.6...
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