christinemayr.bsky.social
Scientist interested in 3’UTRs and mRNA-based translation environments. We study how mRNAs regulate IDR conformations and protein functions. MSKCC in NYC
👤 Joined on 13 November 2024
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@christinemayr.bsky.social"We show here that the protein sequence is insufficient for the biogenesis of fully active IDR-containing transcriptional regulators in cells, suggesting that mRNA 3′ UTRs control their activity by preventing co-translational misfolding" doi.org/10.1016/j.ce...
Show PostSuper important new paper out from @christinemayr.bsky.social 's lab out in Cell. mRNA 3′ UTRs chaperone intrinsically disordered regions to control protein activity: Cell www.cell.com/cell/fulltex...
Show PostCongratulations, Christine! Super nice work!
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