Unterholzner Lab
unterholznerlab.bsky.social
Our group at @BLSLancasterUni investigates how the innate immune system detects infection and injury. We like DNA sensing, host-pathogen interactions and cancer immunology.
👤 Joined on 28 February 2025
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- 28 Şub 2025, 22:55
🎉 Bluesky'e katıldı - İlk kullanıcı adı:
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Paper Alert! Here is a new paper from our group published in @narjournal.bsky.social from the excellent efforts of James Tollitt funded by NWCR. Please take a look: academic.oup.com/nar/article/...
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Supremely excited to share our new paper in @natcellbio.nature.com With an updated genetic cGAMP reporter, we reveal that cGAS activation by DNA damage is a rare event, and that cGAS enrichment on intracellular structures cannot be taken as evidence of activation. www.nature.com/articles/s41...
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We set out to map what #RNA binds to immune receptor #MDA5 during #virus infection. Our findings were unexpected: rather than viral, it was host RNA! Excited (translate: frankly, knackered) to share our paper in @natureportfolio.nature.com Nature Immunology! 🔗 www.nature.com/articles/s41... 🧵👇
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The shared principles of human and bacterial antiviral immunity An honor to highlight remarkable discoveries from many labs over the past 12 years that unite previously disparate fields of how animal cells and prokaryotes defend against viruses. www.nature.com/articles/s41... rdcu.be/fzwyB
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I am happy to share our latest paper on human PIF1, a wonderful collaboration with Raphael Guerois, Ralf Seidel and Ulrich Rass and their teams. Human PIF1 is quite different from its yeast counterpart. Congratulations to Akshay Jayachandran, the first author. genesdev.cshlp.org/content/earl...
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