zierlab.bsky.social
Genome Stability and Innate Immunity Lab at the Institute of Cancer Research, London https://www.zierhutlab.org/
👤 Joined on 27 September 2023
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@zierlab.bsky.socialExcited to share our next steps in pursuing ALC1 as a safe therapeutic target. We show that ALC1 loss expands PARP inhibitor sensitivity in homologous recombination-proficient, Cyclin E1-high cancers with minimal impact on non-cancer fallopian tube cells. link.springer.com/article/10.1...
Show PostRead parts of this today. Very useful.
Show PostFall's arriving but Sunday was a lovely day in NC. We headed to Hanging Rock State Park. We'd been there many times but never took the trail up to Hanging Rock itself, so we joined hundreds of other folks on the way up. It started chilly but warmed up. 1/n
Show PostTogether with other scientists I’m suing the 🇺🇸 US National Institutes of Health for violating our 1st Amendment rights & censoring our health science. I’m ready to shine a light on the darkest days. Buckle up, read on. This gets pretty wild… THREAD
Show PostOur lab is obsessed by hidden biology - protein products central to understanding how our cells function, but missing from standard genome annotations. Introducing new work from post-doc Eric Smith on alternative translational isoforms for heterochromatin protein 1. www.biorxiv.org/content/10.6...
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