lukyfiedler.bsky.social
PhD student at ISTA, Swimmer, Auxin, Excited about cells and genomes, Cambridge Biochemistry BA & MSci 🏳️🌈🌱
👤 Joined on 06 June 2025
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playing with a figure for a pangenome paper. left, a random 500kb of the maize genome, with insertions above and deletions below the reference. insertions square-root scaled. right, a random 50kb segment with insertions shown at scale. the maize genome is a mess, folks!
Show PostHaven't used this is in a while, but a new paper from the group is a good excuse. This is monster of a paper from Sebastian Kaiser about the evolution of non-ribosomal peptides. www.nature.com/articles/s41...
Show PostExcited to share this work from our group, together with the Jackson and Beisel labs! 🧬 We found that aminoacylated tRNA fragments can act as signals to activate bacterial immunity, boosting protection by Cas12a3. Very cool biology, and a great collaboration! www.biorxiv.org/content/10.6...
Show PostOn the origin of morbid curiosity www.scientificamerican.com/article/the-...
Show PostNews: millions of years ago, hybridization gave rise to a tetraploid #fish with two distinct parental subgenomes & this is fascinating: as young barbels develop, they switch from using opsins from one subgenome as larvae to those from the other as adults, fine-tuning their colour #vision! 👁️🌈.
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