Yale Cell Biology

Yale Cell Biology

yalecellbiology.bsky.social

👤 Joined on 03 September 2025

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  • 03 Eyl 2025, 19:56
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @yalecellbiology.bsky.social

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Two new articles from the Reinisch lab @yalecellbiology.bsky.social and De Camilli lab @yaleneuro.bsky.social provide the first complete molecular characterization of VPS13A and C, two proteins involved in neurodegenerative diseases, and show that they can exist in active and inactive states.

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08 July 2026 16:33

Don’t miss this special summer edition of the NPC/transport webinar featuring authors from our recent special @jcellsci.bsky.social issue on the Nucleus!

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Excited to see this study, in collaboration with the De Camilli group @pdc-lab.bsky.social, published in its final format! We resolved the structure of VPS13C and found that it adopts a lipid-transfer-incompetent conformation. We also show that CaM binds VPS13s and may help regulate their function.

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@schvartzman.bsky.social and I wrote a perspective on how dynamic metabolite-protein interactions can shape cell biology, and the open questions this raises about the broad roles of metabolism. It was fun to dig into Zabala-Letona, Carracedo et al.'s story as an example of this! tinyurl.com/4tcnrydm

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hi everybody, asmita here back at it again with another preprint for your attention. excited to share our new fluorogenic speed probes that enable whole cell 3D imaging! 🔬

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