shrinivaslab.bsky.social
Asst. prof at Northwestern ChBE Interested in how molecules and processes are organized and regulated in living cells | physics, math, engineering, and computation (mostly) for biology shrinivaslab.com
👤 Joined on 13 September 2023
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@krishnashrinivas.bsky.social@krishnashrinivas.bsky.social → @shrinivaslab.bsky.socialWe saw your paper with great excitement in our lab this week! If there is an interest to exchange ideas, or even talk about how one could experimentally build such systems, that would be fantastic.
Show PostExcited to share the first pre-print from our lab!! Check it out here! www.biorxiv.org/content/10.6... We found that many RNA-binding proteins canonically understood to regulate RNA processing can also function like transcription factors and cofactors to directly regulate transcription.
Show PostFinally out in @Cellcellpress! Proteins with long IDRs are prone to misfolding during protein synthesis. This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones. www.cell.com/cell/fulltex...
Show Post1/🧵 Can transcription factor condensate formation be explained without phase separation? Our new preprint introduces SPARK, a simulation tool that reproduces condensate behavior (clustering, fusion, FRAP) from diffusion & binding kinetics alone. Movie: 60 sec FRAP sim www.biorxiv.org/content/10.6...
Show PostBack from parental leave. Thanks to the group for the card, I'm looking forward to the next phase of our science.
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