damianosg.bsky.social
PhD in Computational Biology & ML for Proteins @EPFL https://sites.google.com/view/damiano-sgarbossa
👤 Joined on 07 December 2023
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@damianosg.bsky.socialWith this, the last bit of my PhD at @embl.org is finally out! We developed salad (sparse all-atom denoising), a family of blazing fast protein structure diffusion models. Paper: nature.com/articles/s42256-… Code: github.com/mjendrusch/salad Data: zenodo.org/records/14711580 1/🧵
Show PostTwo exciting openings with us! 🤖🧬🆎🧫💉 - AI Scientist 👉 lnkd.in/eDXHH4E8 - AI Scientist, Drug Creation 👉 lnkd.in/eEvGyaTR You'll work on antibody sequence/structure design, antibody-antigen co-folding, antibody-antigen binding prediction, physics-based methodologies, and more! DMs welcome!
Show Post[1/8] 📄 New preprint! With Gionata Paolo Zalaffi & Anne-Florence Bitbol, we introduce ProteomeLM, a transformer that processes entire proteomes (prokaryotes and eukaryotes), enabling ultra-fast protein–protein interaction (PPI) prediction across the tree of life. 🔗 www.biorxiv.org/content/10.1...
Show PostNew preprint of @trono-lab.bsky.social and my PhD work! By modulating SWI/SNF remodeling at ancient transposable elements - LINE/L2s and SINE/MIRs, a "noncanonical" KZFP called ZNF436 protects cardiomyocytes from losing their identity. 🫀heartbeat on 🔁 repeat www.biorxiv.org/content/10.1... #TEsky
Show PostOh this is pretty cool 😃 ESM-C protein language model in JAX+Equinox!
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