sharon greenblum

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• Simon Roux@simrouxvirus.bsky.social31/10/2026 03:19

  And 16 months later, the "global CRISPR" story is now in published form \o/ The original thread at the time of this first pre-print (bsky.app/profile/simr...) describes the dataset and analysis, which has not really changed too much.

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• Mark Bitter @markcbitter.bsky.social15/10/2026 01:05

  New Perspective w/ @petrovadmitri.bsky.social and Paul Schmidt! We ask what evolution-in-action studies tell us about an old question: what genetic variation matters for fitness, and what maintains it? ecoevorxiv.org/repository/v...

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• The Groth lab@grothlab.bsky.social25/02/2026 23:00

  DNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩𝐥𝐢-𝐀𝐓𝐀𝐂-𝐬𝐞𝐪 shows 𝘥𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!

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• Ronan@omalley-regulome.bsky.social15/02/2026 20:20

  New preprint! The same TFs can drive distinct regulatory programs depending on where they bind.
 TSS → rapid stress responses
 Intronic & upstream → cell-type programs
 Enhancer-like CRMs → embryo/meristem programs
 Coding-sequence binding → repression www.biorxiv.org/content/10.6...

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• Innovative Genomics Institute@innovativegenomics.bsky.social07/02/2026 22:10

  IGI's Moi Expósito-Alonso (MOILAB) on his path from growing up in Spain and dreaming of becoming an ecologist to running a research group at Berkeley, studying plant adaptation to #ClimateChange. New from IGI's Emma MacKenzie! Read here: https://ow.ly/g4ph50XAjp4

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