greensi.bsky.social
comp bio research scientist @jgi @lbnl
👤 Joined on 15 November 2024
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@greensi.bsky.socialNew Perspective w/ @petrovadmitri.bsky.social and Paul Schmidt! We ask what evolution-in-action studies tell us about an old question: what genetic variation matters for fitness, and what maintains it? ecoevorxiv.org/repository/v...
Show PostDNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩𝐥𝐢-𝐀𝐓𝐀𝐂-𝐬𝐞𝐪 shows 𝘥𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!
Show PostNew preprint! The same TFs can drive distinct regulatory programs depending on where they bind. TSS → rapid stress responses Intronic & upstream → cell-type programs Enhancer-like CRMs → embryo/meristem programs Coding-sequence binding → repression www.biorxiv.org/content/10.6...
Show PostIGI's Moi Expósito-Alonso (MOILAB) on his path from growing up in Spain and dreaming of becoming an ecologist to running a research group at Berkeley, studying plant adaptation to #ClimateChange. New from IGI's Emma MacKenzie! Read here: https://ow.ly/g4ph50XAjp4
Show PostSequencing methods 🧬 have come a long way from census counts 🔢 to assembling genomes and understanding the functions 🧪 of bacteria and viruses. New review by @jgi.doe.gov's Gitta Szabó, @emileyeloe-fadrosh.bsky.social, Tanja Woyke with @jeffinerca.bsky.social www.nature.com/articles/s41...
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