sharon greenblum
@greensi.bsky.social did:plc:omhnvytwph2ybeh76ok6jg2r
comp bio research scientist @jgi @lbnl
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sharon greenblum (@greensi.bsky.social) ist seit 15 November 2024 auf Bluesky. Das Konto hat 235 Follower, folgt 129 Konten und hat 19 Posts veröffentlicht.
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And 16 months later, the "global CRISPR" story is now in published form \o/ The original thread at the time of this first pre-print (bsky.app/profile/simr...) describes the dataset and analysis, which has not really changed too much.
Post anzeigenNew Perspective w/ @petrovadmitri.bsky.social and Paul Schmidt! We ask what evolution-in-action studies tell us about an old question: what genetic variation matters for fitness, and what maintains it? ecoevorxiv.org/repository/v...
Post anzeigenDNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩𝐥𝐢-𝐀𝐓𝐀𝐂-𝐬𝐞𝐪 shows 𝘥𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!
Post anzeigenNew preprint! The same TFs can drive distinct regulatory programs depending on where they bind. TSS → rapid stress responses Intronic & upstream → cell-type programs Enhancer-like CRMs → embryo/meristem programs Coding-sequence binding → repression www.biorxiv.org/content/10.6...
Post anzeigenIGI's Moi Expósito-Alonso (MOILAB) on his path from growing up in Spain and dreaming of becoming an ecologist to running a research group at Berkeley, studying plant adaptation to #ClimateChange. New from IGI's Emma MacKenzie! Read here: https://ow.ly/g4ph50XAjp4
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