Dave Curtis
@davecurtis314.bsky.social did:plc:5txqv5mf3ggbqvulrp5672ss
Human genetics research at the UCL Genetics Institute, retired psychiatrist. Publications here: https://scholar.google.co.uk/citations?hl=en&user=Vrr4Ig0AAAAJ&view_op=list_works&sortby=pubdate
Sur Bluesky depuis le
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Résumé
Dave Curtis (@davecurtis314.bsky.social) est sur Bluesky depuis le 13 septembre 2023. Le compte a 474 abonnés, suit 78 comptes et a publié 79 posts.
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Interesting, I wonder whether like rare coding variants it would be worth trying to infer consequential compound heterozygous variants by there absence or depletion in UKB. Map pairs that co-occur significantly less then chance without even considering phenotype.
Voir le postwasn't prepared to be emotionally wrecked by an abstract yet here we are
Voir le postI remember the first time I heard about this study a few years ago. "Uh oh, everyone thought, here comes the big genetic explanations of SES differences!" Then they finally did it, and there is essentially nothing there. /2
Voir le postBut you would never know that from a casual reading of this and many similar GWAS of behavioral genotypes. They still breathlessly announce "insights." Here is the insight: genetics are a relatively unimportant factor in income theoretically (h^2) and irrelevant practically (PGS). /3
Voir le postThis raises doubts about the many prior studies using similar data and models to recover in-credible accuracies in very small samples.
Voir le post
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