Dave Curtis
@davecurtis314.bsky.social did:plc:5txqv5mf3ggbqvulrp5672ss
Human genetics research at the UCL Genetics Institute, retired psychiatrist. Publications here: https://scholar.google.co.uk/citations?hl=en&user=Vrr4Ig0AAAAJ&view_op=list_works&sortby=pubdate
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Dave Curtis (@davecurtis314.bsky.social) ist seit 13 September 2023 auf Bluesky. Das Konto hat 474 Follower, folgt 78 Konten und hat 79 Posts veröffentlicht.
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Interesting, I wonder whether like rare coding variants it would be worth trying to infer consequential compound heterozygous variants by there absence or depletion in UKB. Map pairs that co-occur significantly less then chance without even considering phenotype.
Post anzeigenwasn't prepared to be emotionally wrecked by an abstract yet here we are
Post anzeigenI remember the first time I heard about this study a few years ago. "Uh oh, everyone thought, here comes the big genetic explanations of SES differences!" Then they finally did it, and there is essentially nothing there. /2
Post anzeigenBut you would never know that from a casual reading of this and many similar GWAS of behavioral genotypes. They still breathlessly announce "insights." Here is the insight: genetics are a relatively unimportant factor in income theoretically (h^2) and irrelevant practically (PGS). /3
Post anzeigenThis raises doubts about the many prior studies using similar data and models to recover in-credible accuracies in very small samples.
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