PessoaBrain
@pessoabrain.bsky.social did:plc:eip2ux2joizj5ek5nqtrmnym
Luiz Pessoa, University of Maryland, College Park Neuroscientist interested in cognitive-emotional brain Author of The Entangled Brain, MIT Press, 2022 Author of The Cogitive-Emotional Brain, MIT Press, 2013 Neuroscience & Philosophy Salon (YouTube)
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PessoaBrain (@pessoabrain.bsky.social) es un usuario de Bluesky que se unió el 12 agosto 2023. Tiene 9.916 seguidores, sigue a 695 cuentas y ha publicado 2.600 posts.
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And, before @neurosutras.bsky.social brings this up (because he is one of THE experts), the "millisecond" aspect of the original statement is quite debated with behavioral timescale synaptic plasticity, which acts on longer timescales.
Ver postIn the end, it depends what you want to transmit. You could say that there are some ideas how this could work, but they are subject to debate and ongoing research. But I understand that you don't want to write in your book everywhere "this is not understood" ;-)
Ver postOne concern is what Dan mentioned (diversity of plasticity rules). Then the postsynaptic "firing" does not seem to be necessary - rather postsynaptic depolarization, often induced by a burst.
Ver postIt's still useful to understand that what goes on pre- and postsynaptically can change the synaptic weight. But it would be fair to concede that there is no simple principle that describes this for all (or most) neurons.
Ver postThe Selfish Gene, 50 years on — it’s time for an update www.nature.com/articles/d41... - an interesting piece by @nccomfort.bsky.social, but peppered with red herrings, IMO...
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