Mel Eckersley-Maslin

meleckmas.bsky.social

17 October 2026 01:12

We often say cancers reactivate embryonic programs, but how often does this happen? and is it always bad? In this study, we develop EmbryoRadar to detect widespread expression of preimplantation transcriptional programs across all cancers, with varied patient outcomes www.biorxiv.org/content/10.6...

Gerlich Lab

gerlichlab.bsky.social

17 October 2026 01:12

Our latest paper is out in @embojournal.org! Chromatin compaction is a hallmark of apoptosis, but the mechanism & function of this process was unclear. We show apoptotic compaction is required to prevent fragmented DNA from spreading beyond the dying cell, and is driven by histone deacetylation.

Epigenetics at Helmholtz Munich

epihmgu.bsky.social

15 October 2026 20:44

Your Life. Your Genes. Join our Helmholtz Munich Epigenetics Community at Deutsches Museum! 🔬 6–8 Nov: Hands-on exhibition exploring lifestyle, genes & health. 💬 6 Nov, 17:30: Public discussion: “Our Lifestyle – Its Impact for Today and Tomorrow?” in German. Bring your curiosity, family & friends!

Agata Stepien

agatakstepien.bsky.social

15 October 2026 20:43

Two steps in gene expression that should move together… don’t. In our new paper we show that pre-mRNA cleavage and RNA polymerase II (RNAPII) termination shift in opposite directions – with a surprising link to gene expression and cancer cell vulnerability. Read more here: tinyurl.com/3pkeuctp

Harmit Singh Malik

harmitmalik.bsky.social

11 October 2026 11:17

Most animal species pack sperm DNA with protamines instead of histones. Protamines are essential for male fertility. They are among the fastest-evolving genes in animals. That makes little sense. We think we know why, in a new paper led by @ching-hochang.bsky.social. www.science.org/doi/10.1126/...