Sara Šepić

sarasepic.bsky.social

22 October 2026 18:18

Very happy to share my PhD work is now published in Nature Communications @natcomms.nature.com 🥳🤗 Check out how a single subunit of megadalton E3 ligase assembly is capable of recognizing three different degradation signals! doi.org/10.1038/s414...

Alina Thielen

alinathielen.bsky.social

12 October 2026 20:09

I am thrilled to share that my PhD work is now published online in Molecular Cell! 🎉 www.cell.com/molecular-ce... Have a look if you like to learn how the essential amino acid tryptophan directly controls the stability of its metabolic enzyme TDO2 besides its role as a substrate!

Lillie Bell

lilliebell.bsky.social

12 October 2026 13:19

Happy to share my PhD work on the regulatory mechanism of E3 ligase RNF213! RNF213 is not a monomer, but a dimer that switches between inhibited and activated states in an ATP-dependent manner. We tracked the activation mechanism and showed how disease mutations can destabilize the inhibited state.

Vytaute Boreikaite

vytaute.bsky.social

08 October 2026 12:14

I’m very excited to share my postdoc work in the @plaschkalab.bsky.social, where we investigated the very final act of splicing – spliceosome termination, revealing the stepwise dismantling of the spent spliceosome www.nature.com/articles/s41... (1/11)

IMP

impvienna.bsky.social

07 October 2026 20:08

Researchers from our Plaschka lab expected one molecular motor to dismantle the cell’s RNA-editing machine. Instead, they found three. Like three hands untying a knot, the motors act in sequence to take the spliceosome apart: https://bit.ly/4AQnqNQ