Our paper on apoptotic chromatin compaction is out now! Take a look in @embojournal.org, where we investigate compaction in living and dying cells, and show that histone deacetylation prevents DNA from spilling into extracellular vesicles in apoptosis @gerlichlab.bsky.social @imbavienna.bsky.social

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New preprint from the Gurney Lab, on bioRxiv: The Phage Time Continuum: Genome Organization Constrains Anti-CRISPR Success. www.biorxiv.org/content/10.6... I think this is one of the cooler things I'll ever do. Work lead by @sczerwinski.bsky.social he coined the term Phage Time Continuum. 1/10

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ICYMI: New Online! Ubiquitin phosphorylation opens a hatch to a code still largely undeciphered

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Very nice discovery from the Jackson, Bravo and Basel labs. Cleaved tRNA ends, loaded with an amino acid, activate a form of bacterial immunity

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Our latest paper is out in @embojournal.org! Chromatin compaction is a hallmark of apoptosis, but the mechanism & function of this process was unclear. We show apoptotic compaction is required to prevent fragmented DNA from spreading beyond the dying cell, and is driven by histone deacetylation.

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