alicihan.bsky.social
Research Fellow @Memorial Sloan Kettering Cancer Center Ph.D. @The Rockefeller University
👤 Joined on 22 November 2023
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@alicihan.bsky.socialPreprint alert 🚨: We built a CRISPRi screen for a part of the genome that is unusually awkward to perturb: the RNA Pol III transcriptome. Hundreds of tRNA genes, lots of sequence similarity, plenty of redundancy... Turns out the biology had a few surprises for us 👇 www.biorxiv.org/content/10.6...
Show PostCongrats Javokhir! Hopefully new world champion! #FIDEcandidates
Show PostYoungest player in the tournament. No previous Candidates experience. 1st place after four rounds - GM Javokhir Sindarov 🇺🇿
Show PostuPAR CAR T cells eradicate primary and metastatic solid tumors with minimal myelodepletion by targeting both tumor cells and the stroma in preclinical models @cellcellpress.bsky.social @lowelab.bsky.social @mskcancercenter.bsky.social @columbiauniversity.bsky.social www.cell.com/cell/fulltex...
Show PostWe are now excited to move this forward in prospective trials of patients with CDK4/6 independent cancers & high leukemia risk. Thank you to the Neil Hirsch Foundation, @break-cancer.bsky.social , @ash.hematology.org , LLS, Edward P. Evans MDS Foundation, NCI, NHLBI, and V Foundation for support.
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