BindCraft2 v1.0.4 has been released: with significantly improved VHH, scFv, ARP, and induced fit targeting. WE also improved speed and code stability. Try your difficult campaigns again. Great work by @erikmaeots.bsky.social , Leonardo Tredese and @liza-ch.bsky.social

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Struggling to choose a pixel size for your cryo-ET acquisition? Worry not: super-resolution processing can take in situ subtomogram averaging beyond physical Nyquist! We reached 2.8 A loc-res of a ribosome dataset with 4.78 A physical Nyquist limit! Our new preprint 👇: doi.org/10.64898/202...

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Really cool work from my previous colleagues Edo and Jenia developing tools to combine cryo-volume EM and cryo-ET!

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Our new collaborative paper on how PACRG and FAP20 synergistically stabilize microtubule doublets! Brilliantly led by Daria Khuntsariya, with cryo-ET by Umut Batman and subtomogram averaging and analysis by Souradip Mukherjee and Florent Lemaitre. Congrats to all! www.nature.com/articles/s41...

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When imaging at high mag using cryo-ET, field of view reduces. How to overcome this limit? How do we get a "bird’s-eye view" without compromising resolution? Our very own @HamishBrown has a solution to this: “montage tomography with a rectangular beam!” www.biorxiv.org/content/10.6...

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