ICYMI: New online: Single-molecule chromatin tracing reveals a diversity of megabase heterochromatin domains

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New preprint from Dodonova lab 🔔! Capturing multiple states by cryo-EM❄️, we show for the first time how archaeal RNA Polymerase engages a nucleosome and forms direct contacts with histones! 🧬 Great work by Gabriele & a fantastic collaboration with Dina Grohmann! 🧵 www.biorxiv.org/content/10.6...

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🤩On Thursday, October 1, we are pleased to welcome Patrick Heun. He will be giving a talk entitled "Centromere Function - Unique Solutions for a Unique Genomic Region" 📅 October 1 🕐 1:15 PM ➡️Lynen Lecture Hall We’re very much looking forward to welcoming him, everyone is invited!🤗 @tuda.bsky.social

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Frank Nijpels from VitriMatics paid us a visit today. Not only did he repair our broken VitroBot Mark IV and returned it in person, he also brought some extremely cool tools ❄️ for reliable cryo-EM grid freezing 🔬. Check out the VitriClip and the SupraBlot at vitrimatics.com. #cryoEM #cryoET

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⚡Preprint alert⚡ So proud of @amohamed98.bsky.social! Abdallah determined the cryo-EM structure of BRD4 bound to the kinase P-TEFb, defining the molecular basis of this key transcription interaction — and revealing that BRD4 and AFF4 binding are mutually exclusive to P-TEFb. Lots more inside 👇

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