voslab.org
👤 Joined on 21 November 2024
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@seyvos.bsky.social@seyvos.bsky.social → @voslab.org🚨 New preprint! We looked at how information from high-throughput experiments (RNAcompete, RNA Bind'n'Seq) can complement structural data for protein-RNA complexes, and used this to question AlphaFold3 modeling specificity. ⬇️ Work from one of the main PhD projects of @yoannfauconnet.bsky.social 👏
Show Post🔥Preprint alert!🔥 RNase E-dependent guide generation and activation of the SPARMA defense system Read the thread by Theo on how the short pAgo system SPARMA works, how pAgo guide RNAs are generated, and how pAgo autoimmunity is prevented. Preprint here: www.researchsquare.com/article/rs-1...
Show PostHere the latest of our research on #SMC complexes and in particular Condensin II and its timely activation at #mitosis. Particularly proud of this one, all authors and research from amazing @humantechnopole.blsky.social ! kudos to superstar Postdoc @aleborsellini.blsky.social rdcu.be/Cn2SBGxH54ka
Show PostExcited to share our next steps in pursuing ALC1 as a safe therapeutic target. We show that ALC1 loss expands PARP inhibitor sensitivity in homologous recombination-proficient, Cyclin E1-high cancers with minimal impact on non-cancer fallopian tube cells. link.springer.com/article/10.1...
Show PostCheck out our new preprint led by @mileshuseyin.bsky.social unexpectedly discovering Polycomb 3D interactions that persist without cPRC1. Also look out for Miles who is on the faculty job market!
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