Giacomo Donati
giacomodonatijd.bsky.social
Group leader, Prof. @ University of Turin | RNA - chromatin - stem cell plasticity - memory in epithelial cells - wound healing - epithelial tumorigenesis - cancer invasion | www.donatilab.org | Ex @cruk-ci.bsky.social @KCLstemcells
👤 Joined on 24 February 2025
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- 24 Şub 2025, 18:18
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ribosomologists & translationists take note 👇 #MicroSky
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Lovely work from the Gottardi lab revealing new insights into how robust connections between cell-cell junctions and the actomyosin cytoskeleton are constructed and regulated 🧪
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Officially 19 years as a PI. Countless questions. Endless whiteboard scribbles. One enduring obsession: discovering things nobody knew yesterday in a place with an AMAZING mission and unbelievable colleagues. Still living the dream. 💡🔬
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Clegg, @shawnferguson.bsky.social et al. @yalecellbiology.bsky.social show that LRRK2 integrates distinct lysosomal stress signals through stimulus-specific combinations of interactions with Rab GTPases and GABARAP. rupress.org/jcb/article/... #Lysosomes #CellSignaling #Disease #Organelles
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NEW PAPER: How do we make resilient #epithelial barriers? We find that a key #mechanosensitive protein relies on force-dependent unfolding AND phosphorylation to recruit effectors that progressively build #cell-celljunctions. A 🧵: 1/11 doi.org/10.1083/jcb....
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