How does a single methyl group activate bacterial defence? Our new preprint, led by @pspatharas.bsky.social in collaboration with the group of @matthiaswilmanns.bsky.social, explains how a single DNA methylation event activates large retron assemblies. www.biorxiv.org/content/10.6...

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Thrilled to share our paper "A conserved GTPase complex gates exocytosis for defence and parasitism across alveolates" Ciliates are fantastic to understand rhoptry exocytosis, and cryo-ET once again reveals so much🤩 Thanks to all who contributed. @martacova.bsky.social @yiweichang.bsky.social

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A decade ago, Phil Cleves became the first person to genetically modify #coral. Now, he's trying to figure out how to save reefs and the magnificent ecosystems they host from #ClimateChange. Learn more about IGI's newest investigator: ow.ly/fK9F50ZG9s5 Video by @shumpeim.bsky.social

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Incredibly proud of Messi Haile @mehsehret.bsky.social, a founding member of the Ho Lab, for her beautiful work uncovering the inner workings of a central piece of the malaria parasite invasion machinery: the malarial moving junction, out today in @cellpress.bsky.social! tinyurl.com/4p3md2eb 🦠❄️🔬

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1/5 How much phosphorylation can a single kinase deposit? In our new study with @typaslab.bsky.social out in @nature.com, phage T7's kinase (T7K) modifies almost all the E. coli proteome + more densely than all ~500 kinases do our own proteomes 🤯 www.nature.com/articles/s41...

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