cmholab.bsky.social
Structural Biologist • Biochemist • Parasitologist • Co-host of ThePlungePodcast theplunge.org • Assistant Professor @ Columbia • Cryo electron microscopy/tomography of malarial membrane protein complexes. #teamtomo #cryoET #cryoEM #malaria cmholab.org
👤 Joined on 16 November 2024
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@cmholab.bsky.socialthrilled to share that my main phd project is finally out in @natcomms.nature.com we present high-resolution structures of RyR1 in native membranes across multiple functional states by both cryo-ET/StA #TeamTomo and SPA! paper: www.nature.com/articles/s41... and a thread below⬇️⬇️⬇️
Show PostCryo-EM peeps are living the dream www.science.org/doi/10.1126/...
Show PostSailing to a deeper understanding of malaria parasite invasion
Show PostExtraordinary work by Jess Mella. In a technical tour de force she got over nearly 20k variants into hipscs to study the effects in an important nuclear envelope protein LMNA. She used it to dive into cell, structure, and human genetics biology. Keep an eye on her and her future is bright!
Show PostExcited to share this work from @darbly.bsky.social's lab and my lab with @davidhildebrand.bsky.social @briandepasquale.bsky.social and many others! It turns out that the sensory neurons that detect CO2 in Aedes aegypti mosquitoes have lots of recurrent connections! 🦟👃🌟
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