nathanieldhess.bsky.social
PhD Candidate at Princeton University Chemical and Biological Engineering Department Biomolecular condensates, biophysics, and molecular simulations Member of the Joseph Group (https://josephgroup.princeton.edu/) Princeton '22-Present | Penn '18-'22
👤 Joined on 20 January 2025
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@nathanieldhess.bsky.social📣 The Singh Lab opens at Fox Chase Cancer Center in Spring 2027, where I will be starting as an Assistant Professor!📣 Excited to continue studying how protein biophysics shapes drug response. I am hiring across all levels and disciplines! Apply on the "Join" page ( & spread the word!): singhlab.bio
Show PostNo predefined reaction coordinate. No mechanistic guesswork. No massive sampling campaign. Gen-COMPAS reconstructs biomolecular transition pathways from endpoint structures alone. Protein folding, allostery, membrane transport. Now in Nature. @nature.com @springernature.com
Show Post1/ Do cells use phase separation to adapt biosynthetic output to changing demands? In our new preprint, we show that under nutrient limitation, the nucleolus enters a reversible ‘hibernation’ state that slows ribosome biogenesis. See doi.org/10.64898/202...
Show PostNew #RibackLab preprint! The nucleolus's biophysical properties aren't fixed—they're tuned to energy availability. Under nutrient limitation, nucleoli hibernate: stronger interactions, slower rRNA transport, rapid reversal upon refeeding. Led by incredible postdoc @evdokiiap.bsky.social 🧵👇
Show PostA massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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