The Groth lab

The Groth lab

grothlab.bsky.social

The Anja Groth group in Copenhagen studies chromatin replication, epigenetic memory and (epi)genome stability in the context of mitotic cell division

👤 Joined on 18 November 2024

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  • 18 Kas 2024, 21:18
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @grothlab.bsky.social

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Next week's lab journal club paper!

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🧬 How is MCM2-7 switched on? Our paper shows DDK phosphorylation exposes Sld3-binding sites on Mcm4/Mcm6. Sld3-Cdc45 then delivers Cdc45 to Mcm2/Mcm5, driving CMG assembly. In summary, our work explains why MCM2-7 phosphorylation is needed to turn on replication. www.nature.com/articles/s41...

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JIT 4 summer, the latest preprint from our lab, brilliantly led by @kaitezhang.bsky.social w/ support from Collepardo lab (@juliamaristany.bsky.social / @janhuemar.bsky.social). www.biorxiv.org/content/10.6... describes a new single-molecule epigenomic method, & discoveries it enables ... (1/n)

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Delighted to have been awarded a Laboratory Efficiency Assessment Framework (LEAF) Gold certification at Danish Cancer Institute (DCI). Sustainability is an integrated part of how we run the lab, reducing environmental impact without compromising research excellence.

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Very cool study uncovering how stem cells pass on imprints to progeny in vivo from. @thefuchslab.bsky.social @danapeer.bsky.social drawing from beautiful work done by @grothlab.bsky.social on epigenetic inheritance and the mechanisms of information transfer through cell division.

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