🚨New preprint! Ligands at the same GPCR can produce wildly different signaling outputs. Why? We built a mutational scanning platform to measure ~10,000 µOR variants across 15 opioids, yielding ~400k measurements of how sequence and ligand chemistry set signaling. www.biorxiv.org/content/10.6... 1/10

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Spectacular paper from @seth-shipman.bsky.social out in Mol. Cell. The perfect journal club paper. Reverse transcribed ssDNA derepresses translation of a retron antiviral protein: Molecular Cell www.cell.com/molecular-ce...

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Interviewer: Can you explain this gap in your CV? Scientist: I was trying to move a figure in Microsoft Word

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Now that we have moved coasts, I am thrilled to share that the ChromEvo (Raman) lab is officially open at UMass Boston 🎉 We ask how CHROMatin EVOlution leads to functional innovation and we are hiring at multiple levels. Read on and share with folks who maybe interested chromevoramanlab.github.io

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Fragmentation patterns of human telomeric chromatin in plasma cfDNA www.nature.com/articles/s41...

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