lucapinello.bsky.social
Computational methods for epigenetic, CRISPR genome editing and single-cell genomics. Associate Professor at MGH / Harvard Medical School. http://pinellolab.org
👤 Joined on 06 December 2023
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@lucapinello.bsky.socialInspired by Gibson cloning, we describe prime assembly, now published, for in cellulo targeted integration of gene-sized DNA fragments using prime editing. www.nature.com/articles/s41...
Show PostHad the best interaction with a randon beer knower at the corner store. Bk: "I know that look. What beer to get." Me: "ya not gonna get fooled by that pickle beer again" Bk: "this is what you need" *points to voodoo ranger imperial juice force ipa* A true scholar and gentleman
Show PostKinetic proofreading as a mechanism for transcriptional specificity: www.biorxiv.org/content/10.6... Very nice follow up to their review from last year genesdev.cshlp.org/content/39/1... Non-equilibrium models may be key to understanding specificity in transcriptional regulation!
Show PostHappy to see this work out now in Genome Biology! Check out the final version here for your FACS DMS needs: link.springer.com/article/10.1...
Show PostGuitar selection of the day. Godin 5th Avenue Kingpin P90. Canadian wild cherry archtop hollowbody. D’Addario E12 Jazz wound G set. @wbderry.bsky.social @chrmosimann.bsky.social @thelovelylab.bsky.social @lucksmith.bsky.social
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