sylvie-noordermeer.bsky.social
Group leader @ LUMC and Oncode investigating cellular mechanisms protecting genome integrity with a specific interest in DNA double-strand break repair. Music and outdoor lover
👤 Joined on 10 January 2025
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@sylvie-noordermeer.bsky.social@lucievleeuwen.bsky.social, a talented postdoc in my lab, in collaboration with the @hayleysharpe.bsky.social and Dansen lab, developed a variety of fly lines with redox sensors in different subcellular compartments, revealing distinct H2O2 patterns during development. Read more below!
Show PostHappy to share our new paper out today @cp-cell.bsky.social. Great collaboration between @andrewblackford.bsky.social and my lab. Congratulations all!
Show PostOur latest work describing DDIAS as a new component of the TOPBP1-CIP2A pathway in mitosis and its requirement for brain development is now published. Fantastic collaboration with @fenaochs.bsky.social, @profstewartlab.bsky.social, Lars Allan Larsen, @tcr-miller.bsky.social, Zafar Iqbal & others
Show PostAmazing collaboration with the @andrewblackford.bsky.social @fenaochs.bsky.social and Zafar Iqbal on the identification of DDIAS as a new mitotic repair factor that is mutated in a novel chromosomal instability syndrome. www.cell.com/cell/fulltex...
Show PostNew work from the lab! We report that DDIAS is a downstream effector of CIP2A-TOPBP1 in mitosis that suppresses ssDNA to preserve genome integrity. From the great @yiboxue.bsky.social and many collaborators! Free link: authors.elsevier.com/a/1nfiF3vVUP... Pay link: www.cell.com/molecular-ce...
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