nogaleslab.bsky.social
The Nogales Lab @ UC Berkeley. #CryoEM #Transcription #Microtubules #ChromatinModification Bluesky account managed by lab members.
👤 Joined on 26 November 2024
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@nogaleslab.bsky.socialExcited to see our recent work on the structural mechanism of α/β-tubulin biogenesis featured on the #CryoSPARC blog! 🎉 Many thanks to the team at @structurabio.bsky.social Biotechnology for highlighting both the study and the #cryo-EM workflow that made these structures possible. Read more here:
Show PostHow do #tubulin dimers assemble and disassemble to form the #microtubule #cytoskeleton? Our recent #cryo-EM structures, published in #ScienceAdvances, demonstrate the processes of tubulin biogenesis and degradation. Click on the video and link below to learn more! www.science.org/doi/10.1126/...
Show PostHappy to share my new paper from the @nogaleslab.bsky.social, combining #cryoEM and #cryoET to solve how Kinesin-4 KIF21B tail binds to microtubules! Our work shows how the specialized tails of KIF21 kinesins allow both #microtubule attachment and crosslinking. www.biorxiv.org/content/10.6...
Show PostThrilled to share our latest work, led by @aryantaheri.bsky.social and Julia Peukes! Using cryo-EM and cryo-ET, we reveal how KIF21B’s distal tail engages multiple tubulin dimers along a protofilament, enabling persistent microtubule attachment and crosslinking. www.biorxiv.org/content/10.6...
Show PostWell this is a bit cool 😎
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