vseplyarskiy.bsky.social
Assistant Professor UTSW; Mutagenesis, Population genetics, Evolution in somatic tissues and on phylogenetic tree
👤 Joined on 15 November 2024
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@vseplyarskiy.bsky.socialIf you want a quick break from human genetics at #ASHG26, drop by poster 7023W tomorrow afternoon. I'll be presenting some new work about the transgenerational effects of DNA damage in worms. (It's actually relevant to human germline mutation, I promise).
Show PostA genome-scale genetic interaction map of HAP1 reveals ~89,000 interactions across ~4 million gene pairs, shedding light on gene co-essentiality and cellular functions. PMID:42049019, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00345-4 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Show PostMy lab will be at ASHG in Montreal next week with talks and posters on gene expression diversity, chromosomal abnormalities in pregnancy loss, and somatic evolution in the blood. Hope to see you there! 🧬 @michaeltassia.bsky.social @aabiddanda.github.io @geneticssociety.bsky.social #ASHG26 #ASHG2026
Show PostYoutube channel got hacked yall Cant get ahold of a human for support, lmk if ya got a hookup I suppose
Show PostPhylogenetic conservation scores have long been used to identify selection targets in the genome. With machine learning, they take a new form and will likely grow in popularity. @apragsdale.bsky.social and I investigate their relationship with mutation rates www.biorxiv.org/content/10.6...
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