Shicheng Guo
shihcheng.bsky.social
Senior Director, Translational Genetics and Data Science, Translational Medicine | Data Science | Computational Biology | Drug Discovery. Opinions are my own! Linkedin: https://www.linkedin.com/in/shg047/
👤 Joined on 14 November 2024
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- 14 Kas 2024, 16:22
🎉 Bluesky'e katıldı - İlk kullanıcı adı:
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Our lab will present at #ASHG2026 and #IGES2026 with 1 symposium, 4 talks, 2 lightning talks, and 5 posters on cardiometabolic genomics and proteomics. We’d love to see you there! ASHG schedule:
Show PostNew study maps ~89,000 genetic interactions in HAP1 cells from ~4M CRISPR perturbations, revealing hierarchical modules that clarify gene co-essentiality. PMID:42049019, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00345-4 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Show PostThe cGAS-STING pathway detects dsDNA, linking innate immunity to stress responses, influencing 5 key areas: antiviral defense, tissue homeostasis, antitumor immunity, and inflammatory disorders. PMID:42349382, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00650-1 #Medsky #RNA 🧪
Show PostA new model reveals how physical constraints shape the intricate topology of mammalian cortical connectomes, highlighting unique regional connectivity profiles. PMID:42361798, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00648-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Show PostNuclear and cytosolic proteomics of NSCs reveal abundant cytoskeletal proteins like MAP1B, which shuttle to the nucleus, linking microtubule dynamics to cellular fate and disease. PMID:42276043, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00578-7 #Medsky #Pharmsky #RNA #ASHG 🧪
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