Simone Mattei

simonemattei.bsky.social

20 October 2026 17:47

Struggling to choose a pixel size for your cryo-ET acquisition? Worry not: super-resolution processing can take in situ subtomogram averaging beyond physical Nyquist! We reached 2.8 A loc-res of a ribosome dataset with 4.78 A physical Nyquist limit! Our new preprint 👇: doi.org/10.64898/202...

Luuk Loeff

lloeff.bsky.social

19 October 2026 19:06

Exciting times for cryo-EM in NL 🇳🇱! As part of EMPower, two new Titan Krios G5 microscopes have been installed at NeCEN in Leiden and Utrecht. First benchmarks with ApoF reached 1.12 Å resolution 🤯. Looking forward to seeing all the exciting science these microscopes will enable! 🔬

pilarcossio.bsky.social

14 October 2026 20:31

1/5 Cryo-EM gives high-resolution RNA structures, but only when high Mg²⁺ freezes out their motion. At physiological conditions, RNAs are dynamic and 3D reconstruction fails. Can we still learn their folding equilibria? New preprint: yes, straight from the raw particle images👇

Lars-Anders Carlson

lacarlson.bsky.social

14 October 2026 06:34

Recently, a paper that my group co-authored was retracted (PMID: 38635626). Since I was not corresponding author of the paper, I will refrain from longer deliberations, but I also don't want to sweep it under the rug. 1/3

Lennart Pagani

lpagani.bsky.social

08 October 2026 07:25

Check out our new preprint! We describe conformation-specific nanobodies that allow us to study Guanylate-binding proteins and target different stages of their assembly. We shed some new light on current models and hypotheses!