lloeff.bsky.social
Principal Investigator at Leiden University Medical Center Host-Defence | Structural biology | Single-molecule Biophysics http://www.loefflab.com
👤 Joined on 11 December 2023
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@lloeff.bsky.socialThe human gut microbiome primes fever after vaccination | Science www.science.org/doi/10.1126/...
Show PostLoL-align is out in @natmethods.nature.com! It aligns protein structures without superposition. More sensitive than TM-align and DALI, producing better alignments 5–20× faster. Now available in Foldseek! 📄 www.nature.com/articles/s41... 💾 github.com/steineggerlab/foldseek 🌐 search.foldseek.com
Show PostExcited to share our work on bacterial immune signaling! Our preprint reveals how RNA-guided Cas13 cleaves host tRNAs to generate small-molecule messengers that activate 2TMβ, linking RNA recognition to membrane damage and phage defense. 1/11
Show PostHeads-up! I’ll be starting my research group at MedUni Vienna in January 2027, with postdoc and PhD positions available soon. Looking for people interested in bacteria–phage interactions, bacterial defense systems, and phage anti-defense strategies. Please send your CV: anna.lopatina@univie.ac.at
Show PostA new plant-bacteria immunological connection in the first preprint of our group at @mpi-bio-fml.bsky.social @plantevolution.bsky.social! Straight from the top of Mt. Olympus ⛰️🦅 Led by Eirik @eiriklag.bsky.social, in collaboration with @geminiteamlab.bsky.social www.biorxiv.org/content/10.6...
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