Rafael Pinilla-Redondo (Rafa)
rafomics.bsky.social
Asst. Prof. at Copenhagen University. Excited about phages, plasmids, and bacterial immunity!👨🔬🔬 https://pinillaredondolab.com/
👤 Joined on 26 October 2025
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- 26 Eki 2025, 16:24
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Aminoacylated tRNA tails trigger auxiliary bacterial immunity https://www.biorxiv.org/content/10.64898/2026.10.14.759216v1
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Do you like riddles(and molecular biology)? Maybe you can help me solve this one. We’ve found a short piece of DNA (a plasmid) present in almost all plague samples from the Second Plague Pandemic (1338-1840), but absent in all earlier or later plague cases. www.biorxiv.org/content/10.6...
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Viruses have parasites too. Our new preprint shows how phages use VIPR to silence parasitic satellites, and how the satellites fight back with its own decoy VIPR RNAs that redirect VIPR to DNA REP elements in the host genome!! www.biorxiv.org/content/10.6...
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Very nice discovery from the Jackson, Bravo and Basel labs. Cleaved tRNA ends, loaded with an amino acid, activate a form of bacterial immunity
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I’m very excited to have this preprint out! There will be more work on the Phage Time Continuum coming soon!
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