vindignilab.bsky.social
Washington University in St. Louis https://vindignilab.wustl.edu/
👤 Joined on 22 November 2024
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@vindignilab.bsky.social‼️ Excited to share our new paper out now in @science.org ‼️ We describe a new tetrameric RAD51 paralog complex – XRCC3-RAD51C-RAD51D-XRCC2 – which caps the end of RAD51 filaments. Link: www.science.org/doi/epdf/10.... Thread ⬇️ (1/8)
Show PostAmong the anti-recombinases, FIGNL1 rules them all. So much that inactivating it brings BRCA2-deficient cells to life. Who is responsible for RAD51 loading without BRCA2/FIGNL1, check out the paper to find out! Great collaboration with @raychaudhurilab.bsky.social www.science.org/doi/10.1126/...
Show PostTrip to Greina plateau, northern Ticino
Show PostExcited to share our latest preprint by @mihyun-kim.bsky.social showing how DNA incision activities in nucleotide excision are regulated to ensure genomic stability. We show that interactions between TFIIH and XPG control the 5' incision by ERCC1-XPF. www.biorxiv.org/content/10.1...
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