Two new papers from the lab published in The EMBO Journal! link.springer.com/article/10.1... By Kai Walstein, @louisa-hill.bsky.social and others – On role of M18BP1 in CENP-A loading link.springer.com/article/10.1... By Arianna Esposito Verza and others – On mechanism of activation of PLK1

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This just in. So honored and grateful...

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We are excited to share that our latest work from the lab aimed at understanding how the tRNA nuclease SLFN11 is activated in response to DNA damage and replication stress has just been published in @natcellbio.nature.com! Open access link: www.nature.com/articles/s41... (1/9)

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New lab preprint! ERCC6L2 disease is a recessive bone marrow failure syndrome caused by mutations in the putative DNA helicase ERCC6L2. Using mouse genetics, biochemistry and AF3 we uncover ERCC6L2-MRI as a KU-regulatory complex stimulating NHEJ at staggered DSBs: www.biorxiv.org/content/10.1...

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Our protocol for imaging-based quantification of RNAPII clearance during transcription-coupled DNA repair is now online. 👇 Well done, Bram, Diana, and Paula! star-protocols.cell.com/protocols/45...

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