Aanchal Mishra

Aanchal Mishra

origichals.bsky.social

Human | Learner | PhD researcher studying SUMOylation (SUMO:SIM interactions) using Biochemistry and Structural Biology approach @msuskiewicz.bsky.social lab @cnrs.fr

👤 Joined on 18 November 2024

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  • 18 Kas 2024, 18:46
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @origichals.bsky.social

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We should add though that ZBTBs have been seen to be SUMOylated, notably ZBTB33/KAISO in this great paper, but what we claim is the unusually high intrinsic SUMOylability of these proteins in vitro.

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Stunning cryo-ET analysis from the Harrison Lab capturing every stage of how non-membrane viruses infect animal cells www.science.org/doi/10.1126/...

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As always, I include this thread in a slightly extended version on my blog msuskiewicz.github.io/blog/, where I hope I will write about more TF-related papers in the near future (I have been writing too much about AI instead!).

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Check out our new article if you are interested in disorder-mediated protein interactions, AlphaFold-based structural modeling and variant characterization: Https://rdcu.be/fw2oz Dx.doi.org/10.1038/s41594-026-01846-z

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Happy to share the first preprint out of the Nomburg lab! Many aspects of cellular immunity are shared across the tree of life. Here, we show that some of these conserved aspects of cellular immunity are mirrored by conserved effectors of immune antagonism. Thread below! 1/15

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