Jovana Maksimovic
jovmaksimovic.bsky.social
Senior Research Associate in Bioinformatics & Computational Biology in the Oshlack Lab @petermaccc.bsky.social Australia. Mum. Sci-fi nerd. Cat person. Really loves cheese. And dancing.
👤 Joined on 20 November 2024
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- 20 Kas 2024, 05:04
🎉 Bluesky'e katıldı - İlk kullanıcı adı:
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Love your work @jovmaksimovic.bsky.social !!!
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We've thought about including CellSweep! According to their lovely tutorial (cellsweep.readthedocs.io/en/latest/tu...) they actually already recommend removing doublets before using CellSweep so we figured they're aware of the potential impacts their tool has on doublet detection.
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If you’re working with Flex data, be careful when doing ambient RNA correction! It turns out that removing ambient RNA (in particular with decontX), and *then* doing doublet ID, can seriously reduce doublet detection performance ‼️
Show PostEqually happy and terrified to share my first preprint of my PhD! Turns out the order of your scRNA-seq QC pipeline matters more than we thought: removing ambient RNA before doublet detection can reduce doublet detection performance!
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Turns out the order of your scRNA-seq QC pipeline matters more than we thought: removing ambient RNA before doublet detection can reduce doublet detection performance! Our new paper from the amazing PhD student @michellemeier.bsky.social
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